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Bioentopic Natural Retinol-A Creme by Biocentric L Natural Retinol-A Crème with Aloe Vera, Vitamin E and Evening Primrose Oil 1% Retinol (Vitamin A): It was discovered that vitamin A crème reduced wrinkles, pigment spots and helped to reverse the damage from UV rays. First there was tretinon (Retin-A brand) Then there was retinoic acid (Renova brand). Both by prescription only. Both having side effects of irritating the skin. Natural Retinol-A Créme is a sensitive skin formula specifically designed to give the benefits without the harsh side effects of a prescription Retin-A. Suggested Use: Cleanse the face, neck and the back of the hands. Thoroughly apply the crème to those areas. Avoid contact with eyes. Contains no sunscreen. This is a concentrated topical treatment. Use sparingly at first to determine correct amount of crème for the face type. May be used day or night. External use only. As with any product, in case of a rash, discontinue use. Active Ingredient: 1% Retinol-A Other Ingredients: A -- $19.95